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| Starting Lineup | Name | Position | B/T | bWAR/ 650 | OPS+ | Years Played |
| 1. | Nap Lajoie | 2B | R/R | 8.1 | 155 | 1902-14 |
| 2. | Tris Speaker | LF (CF) | L/L | 7.5 | 158 | 1916-26 |
| 3. | Manny Ramirez | DH (LF/RF) | R/R | 4.9 | 152 | 1993-2000 |
| 4. | Jim Thome | 1B (3B) | L/R | 5.5 | 152 | 1991-2002, 11 |
| 5. | Larry Doby | RF (CF) | L/R | 5.6 | 140 | 1947-55, 58 |
| 6. | Lou Boudreau | SS | R/R | 6.2 | 121 | 1938-50 |
| 7. | Joe Sewell | 3B (SS) | L/R | 4.8 | 111 | 1920-30 |
| 8. | Kenny Lofton | CF | L/L | 5.6 | 109 | 1992-96, 98-2001, 07 |
| 9. | Sandy Alomar | C | R/R | 2.4 | 92 | 1990-2000 |
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| Bench | | | | | | |
| OF | Earl Averill | CF | L/R | 4.7 | 136 | 1929-39 |
| OF | Hal Trosky | 1B | L/R | 4.0 | 135 | 1933-41 |
| IN | Terry Turner | SS/3B/2B | R/R | 4.1 | 91 | 1904-18 |
| IN | Ken Keltner | 3B | R/R | 3.6 | 112 | 1937-49 |
| C | Steve O'Neill | C | R/R | 3.4 | 91 | 1911-23 |
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| Starting Rotation | Name | | B/T | | ERA+ | Years Played |
| 1. | Bob Feller | | R/R | | 122 | 1936-56 |
| 2. | Addie Joss | | R/R | | 142 | 1902-10 |
| 3. | Stan Coveleski | | R/R | | 129 | 1916-24 |
| 4. | Bob Lemon | | L/R | | 119 | 1946-58 |
| 5. | Early Wynn | | S/R | | 119 | 1949-57, 63 |
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| Bullpen | | | | | | |
| LR | Mel Harder | | R/R | | 113 | 1928-47 |
| RP | Jose Mesa | | R/R | | 117 | 1992-98 |
| RP | Doug Jones | | R/R | | 137 | 1986-91, 98 |
| RP | Bob Wickman | | R/R | | 138 | 2000-06 |
| SU | Eric Plunk | | R/R | | 141 | 1992-98 |
| CL | Cody Allen | | R/R | | 142 | 2012-18 |